Capecitabine Pattern of Use, Febrile Neutropaenia and Treatment Related Death in Asian Cancer Patients
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چکیده
Capecitabine (Xeloda®) is an oral prodrug that is converted to 5-fluorouracil (5-FU) in a three-step enzymatic process, the final stage of which is mediated by thymidine phosphorylase (TP). Significantly higher TP activity has been recorded in a number of human tumour tissues (including colorectal, breast, stomach, cervix, uterus, ovary, kidney, bladder, and thyroid), compared with normal tissue adjacent to the tumour, allowing
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تاریخ انتشار 2015